Systemic Therapy for Acne
Systemic Antibiotics including Tetracycline and its derivatives Doxycycline and Minocycline have been used to treat acne for many years (since the 1950-s). They are still being used to-day, mainly for their anti-inflammatory actions. Other antibiotics, such as Penicillins and Cephalosporins are used more rarely.
Nicotinamide, a Vitamin in large doses, has also been used for a long time to treat acne, again for its anti-inflammatory actions.
For women with resistant acne, Spironolactone, a diuretic with some anti-androgen activity, has been used for several years. Caution must be exercised in following the Potassium level and in absolutely avoiding Pregnancy.
Birth Control Pills have been used with variable success to fight acne.
If everything fails, Accutane is extremely effective, but it has some unpleasant side effects.
Some patients prefer the Photodynamic Treatment with the Isolaz machine as described above, to the Accutane treatment for acne.
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